1118 Examination of usefulness of maintenance therapy with adapalene 0.1%/benzoyl peroxide 2.5% gel and benzoyl peroxide 2.5% gel for acne vulgaris and evaluation of atrophic acne scars using 3D image analysis

نویسندگان

چکیده

Background and Objective: Adapalene/benzoyl peroxide gel (ADP/BPO) benzoyl (BPO) are recommended for the treatment of acne vulgaris during acute inflammatory phase maintenance therapy after inflammation has subsided. As an advantage continued treatment, it is expected that atrophic scar formation will be reduced by maintaining remission The purpose this study was to investigate usefulness with anti-acne drugs its effect on suppression scars. Method, Results: This a multicenter, open-label, randomized, group-controlled observation period 24 weeks. 126 patients were randomly assigned ADP/BPO group (n=40), BPO (n=44), or control (n=42). primary endpoint, success rate 89.2% in group, 87.5% which significantly higher compared (p=0.0006, p=0.0006). number lesions, secondary lower both groups at weeks (p=0.0016, p=0.0482). At weeks, showed significant improvement change count baseline (p=0.0004, p<0.0001). For formation, 3D image analysis parameters not changed but group. Side effects occurred 3 (7.5%) none Conclusion: useful Japanese reduce scars prevent deterioration.

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2023

ISSN: ['1523-1747', '0022-202X']

DOI: https://doi.org/10.1016/j.jid.2023.03.1130